CASE REPORT: A woman in her Early 40’s who has Diminished Ovarian Reserve Requiring IVF with Embryo Banking and PGS.

By Dr. Geoffrey Sher on 12th October 2016

Hi Dr Sher,
I’m 42 years of age. Until very recently, I knew nothing about IVF, and I now find myself in a scramble to optimize my chances with it.

Despite a lifelong dream of having a healthy baby and … Read more

Defining and Addressing an Abnormal Luteal Phase

By Dr. Geoffrey Sher on 10th October 2016

Following ovulation, what remains of the ruptured follicle transforms itself into a structure called the Corpus Luteum (CL) which produces progesterone. The purpose of progesterone is to prepare the uterus to accept and support an early pregnancy until it is … Read more

IVF Should Supplant Tubal Fertility Surgery

By Dr. Geoffrey Sher on 21st September 2016

A progressive increase in success rates with IVF versus tubal fertility surgery has over the last 25 years brought about a shift away from the latter to the former. And so it should be, because even in young women, attempted … Read more

Endometriosis and Immunologic Implantation Dysfunction (IID) and IVF

By Dr. Geoffrey Sher on 20th September 2016

More than half of women who have endometriosis harbor antiphospholipid antibodies (APA) that can compromise development of the embryo’s root system (trophoblast). In addition and far more serious, is the fact that in about one third of cases endometriosis, … Read more

IVF: A Personalized Step-by Step Approach

By Dr. Geoffrey Sher on 15th September 2016

The ability to grow a healthy plant requires that a “good” seed be planted in a “fertile soil” and then be properly nurtured until it can thrive on its own….independent of intervention. Similarly, successful IVF requires the same relationship, only … Read more

IVF: How many tries should be considered before stopping?

By Dr. Geoffrey Sher on 5th September 2016

Because of the emotional, physical, and financial toll exacted by IVF, it is preferable that no one undertake a one shot attempt. If a couple can only afford one treatment cycle, IVF is probably not the right course of … Read more

IVF: The first Choice for Infertile Women 40 to 43 Years of Age

By Dr. Geoffrey Sher on 29th August 2016

Consider the fact that between 40 and 43 of age, the success rate per cycle of treatment with injectible fertility drugs alone, with or without intrauterine insemination (IUI) is 2- 3%. Since it is 6-8 times higher with “conventional” With … Read more

“Unexplained” Infertility : Often a matter of the Diagnosis Being Overlooked!

By Dr. Geoffrey Sher on 8th August 2016

For about 10% of all infertile couples, the cause of the infertility cannot be readily determined using conventional diagnostic methods. Such cases are often referred to as “unexplained infertility.” The truth however is that in most such cases, the diagnosis … Read more

The Role of IVF in Cases of Tubal Damage

By Dr. Geoffrey Sher on 8th August 2016

Tubal damage is one of the commonest causes of infertility. It is most often due to pelvic inflammatory disease (PID) caused by sexually transmitted bacterial infection with chlamydia trachomatis and Neisseria gonorrhea. Acute PID caused by such usually are associated … Read more

Ovarian Stimulation in Women Who have Diminished Ovarian Reserve (DOR): Introducing the Agonist/Antagonist Conversion protocol

By Dr. Geoffrey Sher on 3rd August 2016

The use of GnRH antagonists, as currently prescribed in ovarian stimulation cycles, i.e. the administration of 250mcg daily from the 6or 7th day of stimulation with gonadotropins, is in my opinion problematic when used in women who have diminished … Read more