“As physicians we really need to seriously rethink the basis upon which we recommend IUI!” –GS
Intrauterine insemination (IUI), the injection of sperm into the uterus by means of a catheter directed through the cervix, has been practiced for … Read more
As a woman ages beyond 30 years, the quality of her eggs starts to decline progressively and with it also her fertility potential. By age 40 she is about half as likely to conceive and by her mid forties she … Read more
Polycystic Ovarian syndrome (PCOS) is a common female, hormonal system disorder affecting between 5% and 10% of women of reproductive age worldwide. Women with PCOS may have enlarged ovaries that contain small collections of fluid — called follicles — located … Read more
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The potential for a woman’s eggs to undergo orderly development and maturation, while in large part being genetically determined can be profoundly influenced by the woman’s age, her “ovarian reserve” and proximity to menopause. It is also influenced by the … Read more
Over the past three decades, I have met and consulted with tens of thousands of couples seeking treatment for diverse reproductive issues involving infertility and pregnancy loss. The universal thread that I have encountered is people’s hunger for information when … Read more
When confronted with “unexplained” IVF failures where morphologically good embryos were transferred, the question arises as to whether the problem is due to inherent egg/embryo “incompetence” (which usually equates with an irregular chromosomal configuration [aneuploidy]) or whether it is due … Read more
The bottom line is that because of the traumatic effect of freezing on egg viability and “competency” the statistical chance of each frozen/ thawed egg ultimately resulting in a baby is only at best 6-8%. So, while success rates following … Read more
Whenever IVF fails to resolve reproductive failure, the explanation is almost invariably either: a) embryo “incompetence” (usually …although not always due to the embryo being karyotypically abnormal or aneuploid) or b) implantation dysfunction (anatomical/ immunologic). So…should the transfer of up … Read more
About 10 years ago, Levent Keskintepe PhD and I introduced Comparative Genomic Hybridization (CGH) into the clinical IVF arena, as a preimplantation genetic sampling (PGS) method that enables full karyotyping (numerically chromosomal analysis) of all 23 pairs of an embryo’s … Read more
The Number of Embryos/Blastocysts Transferred & PGT: Effect on IVF Outcome:
Cyclical Estrogen Therapy Prior to Embryo Transfer, in Post-Menopausal Women and those with Prolonged Hypothalamic Amenorrhea can Reduce the Chance of Failed IVF and Miscarriage
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