In the United States, effective treatment of NK/CTL activation associated with either alloimmune or autoimmune implantation dysfunction requires the administration of primarily Intralipid (IL). Such treatment is much more likely to be successful in the case of` autoimmune implantation dysfunction … Read more
Dr. Sher Blog
Official Blog of Dr. Geoffrey Sher
Immunologic Implantation Dysfunction (IID) & Infertility (IID): PART 2-Making a Diagnosis
Currently there are fewer than a dozen immunology reference laboratories in the U.S that are capable of analyzing the required elements with a sufficient degree of sensitivity and specificity as to be reliable in my opinion. These elements include measuring … Read more
IVF-Gestational Surrogacy: An Overview
IVF surrogacy involves the transfer of one or more embryos into the uterus of a surrogate, who provides a host womb and carries the baby to term, but does not contribute genetically to the baby. Typically, the intended mother provides … Read more
Launching Ovarian Stimulation with a BCP: How Does it Affect Response?
One often hears the expressed opinion that the BCP suppresses response to ovarian stimulation. This is not the case, provided that the BCP is overlapped with administration of an agonist (e.g. Lupron, Buserelin, Superfact) for several days leading up to … Read more
Egg Donation-Fashioning Rational Expectations: Preparation; Donor Selection; Using Fresh versus Frozen (Banked) Eggs; Financial/Ethical Considerations; The Process; Outcome!…
For many women, disease, the physiological decline in ovarian reserve (DOR) and spontaneous or pathologically induced menopause will preclude pregnancy using own eggs. For such women, the performance of IVF using the eggs of a chosen young third party (egg … Read more
Recurrent Pregnancy Loss (RPL): Why do I keep losing my Pregnancies and What can be Done?
When it comes to reproduction, humans are the poorest performers of all mammals. In fact we are so inefficient that up to 75% of fertilized eggs do not produce live births, and up to 30% of pregnancies end up being … Read more
Secondary Infertility: Addressing the Root Causes
It is one thing for a woman who has never been able to conceive (primary infertility) to come to grips with undergoing In Vitro Fertilization. It is quite another matter for someone who has successfully achieved a pregnancy in the … Read more
Staggered IVF: An Excellent Option When Advancing Age and Diminished Ovarian Reserve (DOR) Reduces IVF Success Rate
Many physicians treating infertile women over 40 years old who have patent fallopian tubes still opt to start with the least invasive strategy rather than going straight to IVF. This usually begins with the prescribing of oral and then injectable … Read more
The Role of Nutritional Supplements in Preparing for IVF
It is important to nurture and take care of yourself mentally and physically when preparing and going through your IVF journey. This starts with trying to have a positive attitude about what you are about to go through, creating a … Read more
Thyroid autoantibodies and Immunologic Implantation Dysfunction (IID)
Between 2% and 5% of women of the childbearing age have reduced thyroid hormone activity (hypothyroidism). Women with hypothyroidism often manifest with reproductive failure i.e. infertility, unexplained (often repeated) IVF failure, or recurrent pregnancy loss (RPL). The condition is 5-10 … Read more
Recent Posts
Sher-IVF Success Rate
IVF SUCCESS RATE EXPRESSED AS VIABLE PREGNANCY RATE PER EMBRYO TRANSFERRED (PRPE): A PROPOSED NEW PRADIGM FOR IMPROVED AND VERIFIABLE REPORTING OF IVF STATISTICS
Genetically Testing IVF Embryos
A Case for Transferring Blastocysts on Day 5-6 Post-Fertilization Rather Than on Day 2-3 as Cleaved Embryos.
Management of Immunologic Implantation Dysfunction (IID)
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