The numerical chromosomal configuration of a cell is referred to as its karyotype or ploidy. A cell with an irregular chromosome number is referred to as aneuploid while one with a normal karyotype, as euploid. It is predominantly (but not … Read more
Dr. Sher Blog
Official Blog of Dr. Geoffrey Sher
Male Infertility
Male factor problems as a contributing cause of infertility are very common. Male infertility is reported as a factor in 30-50% of infertility cases. In fact, many fertility specialists will recommend a semen analysis as one of the very first … Read more
The IVF Journey: The importance of “Planning the Trip” Before “Taking the Ride”
The objective with In Vitro Fertilization is to consistently transfer competent embryos into a receptive uterine environment. This requires a very individualized and meticulous approach to evaluating and addressing those factors that can influence IVF outcome: All patients/couples should … Read more
Are Injectable Fertility Drugs Safe?
I have all too often heard it said that medical providers knowingly place unsuspecting infertile women at risk of developing cancer through the fertility injectable drugs and treatment they administer and that we knowingly place patients at risk by understating … Read more
Raised Blood Prolactin Levels (Hyperprolactinemia) in Women Undergoing Infertility Treatment
Prolactin is a protein hormone (closely related to human growth hormone) that is secreted by specialized cells in the anterior part of the pituitary gland. In addition, the hormone is also produced and secreted by a broad range of … Read more
IVF Failure and Implantation Dysfunction
Implantation dysfunction is unfortunately often overlooked as an important cause of IVF failure. In the pursuit of optimizing outcome with IVF, the clinician has a profound responsibility to meticulously assess and address this important issue if IVF success is to … Read more
Cervical Incompetence: A Common Cause of Late Miscarriage, Premature Birth and 2nd Trimester Recurrent Pregnancy Loss (RPL)
With cervical Incompetence (CI) the cervix starts to shorten (efface) and dilate too early in the pregnancy giving rise to late (2nd trimester) miscarriage or premature birth. It can occur with first pregnancies (“Primary Cervical Incompetence”) or after a prior … Read more
The Pro’s and Con’s of Preimplantation Genetic Testing (PGT) : It Should be Used Selectively
About a decade ago, I, along with my associate, Levent Keskintepe PhD were the first to introduce full chromosome Preimplantation Genetic Testing (PGT) into the IVF clinical realm to try and identify euploid embryos whose cells contained the required 46 … Read more
Case Report: Treating Hydrosalpinx by Surgical Removal (Salpingectomy) as a Prelude to IVF
Case Report:
**For the purposes of anonymity, I will be referring to the patient as RL throughout this blog.**
RL, a 31-year-old woman, presented with a 7 year history of inability to conceive, in spite of 2 prior fresh and … Read more
CASE REPORT: A woman in her Early 40’s who has Diminished Ovarian Reserve Requiring IVF with Embryo Banking and PGS.
Hi Dr Sher,
I’m 42 years of age. Until very recently, I knew nothing about IVF, and I now find myself in a scramble to optimize my chances with it.
Despite a lifelong dream of having a healthy baby and … Read more
Recent Posts
The Role of IVF in the Management of Infertility Caused by Pelvic Inflammation- Case Report: Can Intralipid/Steroid Therapy be Used Without Undergoing IVF?
Hormonal Supplementation in IVF- A Message on COVID-19
Advising Women who Contemplate undergoing Infertility Treatment and who Test Positive for Hepatitis B Virus antigen (HPV+)
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